Key result
CVD accounts for ~50% of deaths among survivors of breast, prostate, endometrial, and thyroid cancers.
Why the study?
Cardiovascular disease substantially contributes to mortality and morbidity in the growing population of cancer survivors, raising an urge for effective strategies to prevent and treat cardiovascular events in this population.
This review highlights the critical need for effective strategies to prevent and treat cardiovascular events, particularly atherothrombotic manifestations, in the growing population of cancer survivors.
Emphasizes CVD monitoring in cancer survivors; leaves open optimal prevention strategies pending prospective data.
Cancer and cardiovascular disease are leading causes of mortality and morbidity worldwide. Scientific studies show that patients with cancer are at increased risk of developing cardiovascular events, leading to the novel cardio-oncology research field. Growing evidence suggests that cancer and cardiovascular disease are not separate entities but are connected through shared risk factors, pathological mechanisms, and genetic predispositions. Moreover, anticancer therapies such as radiotherapy have been known to further increase the cardiovascular risk in patients with cancer. Due to the significant advances in oncological diagnostics and therapy, the number of cancer survivors has been growing substantially. Nowadays, the majority of patients with cancer dies from non-cancer causes. Cardiovascular disease substantially contributes to mortality and morbidity in cancer survivors. For some cancers, such as breast, prostate, endometrial and thyroid cancer, about half of the patients dies from cardiovascular disease. This raises an urge for effective strategies in preventing and treating cardiovascular events in patients living with and surviving cancer. In this review, we address the evolving data on cardiovascular disease in patients with cancer, with a special focus on atherothrombotic manifestations including myocardial infarction and ischemic stroke.
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Willems et al. (2022) conducted a review in Cancer and cardiovascular disease. Cardiovascular disease substantially contributes to mortality in cancer survivors, accounting for about half of deaths in patients with breast, prostate, endometrial, and thyroid cancer.
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