Key result
Heart failure and thyroid disorders predict up to ~470% greater stroke risk in AFib.
Why the study?
Stroke is an increasing public health issue in developing countries and patients with atrial fibrillation are particularly vulnerable, making identification of stroke prevalence and predictors important to prevent severe complications and death.
What is the prevalence and what are the predictors of stroke among atrial fibrillation patients in Northwest Ethiopia?
Cross-Sectional (n=242)
No
What is the prevalence and what are the predictors of stroke among atrial fibrillation patients in Northwest Ethiopia?
In a cross-sectional study of Ethiopian patients with atrial fibrillation, the prevalence of stroke was 19.4%, with heart failure and thyroid disorders identified as significant risk factors.
These comorbidities were associated with elevated stroke odds in this cohort; hypothesis-generating and should not yet change practice.
INTRODUCTION: Recently, stroke is becoming the major public health problem in developing countries including Ethiopia. Atrial fibrillation patients are the most vulnerable group for the occurrence of stroke. Knowing the predictors and being aware for it is important for preventing severe complications and death. Therefore, the aim of this study is to assess the prevalence of stroke and identifying significant predictors. METHODS: A hospital-based cross-sectional study was performed from 1 December 2018 to 30 September 2019 at University of Gondar Referral Hospital. A total of 242 patients with atrial fibrillation were included in the study. Atrial fibrillation patients were diagnosed by using 12 lead electrocardiographic tracing, in addition to thorough medical history and physical examination and analyzed by the Modular ECG Analysis System (MEANS). We used Epi info 7 and SPSS version 22 software for data entry and analysis purpose, respectively. Both bivariable and multivariable binary logistic regression model were computed to show the relationship of dependent and independent variables. RESULT: The prevalence of stroke among atrial fibrillation patients was 19.4% (95% confidence interval (CI): 14.9-25.2). Patients with heart failure (adjusted odds ratio (AOR): 5.70, 95% CI: 2.50-13.24) and thyroid disorder (AOR: 4.98, 95% CI: 1.47-16.85) are at risk of developing stroke. CONCLUSION: The prevalence of stroke was higher compared with others studies. Patients with heart failure and thyroid disorders were the risk factor for the development of stroke; therefore, physicians and cardiologists may better to consider all these two disorders when they diagnose stroke in patients with atrial fibrillation.
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Gedamu et al. (2021) conducted a cross-sectional in Atrial fibrillation (n=242). Heart failure (AOR 5.70; 95% CI 2.50-13.24) and thyroid disorder (AOR 4.98; 95% CI 1.47-16.85) were significant predictors of stroke among atrial fibrillation patients (overall prevalence 19.4%).
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