Key result
Epicardial stenosis severity (10%, 50%, and 75%) did not affect the index of microcirculatory resistance when corrected for coronary wedge pressure (IMR=22, 23, and 23 U, respectively; P=0.28).
Why the study?
Does epicardial stenosis severity affect minimal microcirculatory resistance in patients undergoing PCI?
Does epicardial stenosis severity affect minimal microcirculatory resistance in patients undergoing PCI?
p-value: p=0.28
IMR is a specific index of microvascular resistance that remains independent of epicardial stenosis severity when collateral flow is properly taken into account.
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IMR remains valid for microvascular assessment independent of epicardial stenosis; leaves open validation in larger PCI cohorts.
Aarnoudse et al. (2004) studied Patients scheduled for percutaneous coronary intervention (n=30). Creation of 10%, 50%, and 75% area stenosis vs. Within-subject comparison across stenosis severities was evaluated on Index of microcirculatory resistance (IMR) corrected for coronary wedge pressure (p=0.28). Epicardial stenosis severity (10%, 50%, and 75%) did not affect the index of microcirculatory resistance when corrected for coronary wedge pressure (IMR=22, 23, and 23 U, respectively; P=0.28).
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