Why the study?
Does epicardial artery stenosis severity affect myocardial microvascular resistance when collateral flow is accounted for in a pig model?
Does epicardial artery stenosis severity affect myocardial microvascular resistance when collateral flow is accounted for in a pig model?
After accounting for collateral flow, the minimum achievable microvascular resistance is not affected by the severity of epicardial coronary artery stenosis.
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Accounting for collaterals shows microvascular resistance unaffected by stenosis; leaves open whether IMR interpretation changes in humans.
Fearon et al. (2004) studied this question.
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