Key result
Asymptomatic carotid stenosis ≥50% had a prevalence of 6.4% in a population-based cohort, was strongly associated with coronary heart disease (OR 8.00), and had a 9.4% biennial ischemic event rate.
Why the study?
What is the prevalence and outcome of asymptomatic carotid stenosis detected by duplex scanning in a general population aged 50-79 years?
Cohort (n=500)
What is the prevalence and outcome of asymptomatic carotid stenosis detected by duplex scanning in a general population aged 50-79 years?
Answers are grounded in this paper and cite their sources.
Asymptomatic carotid stenosis ≥50% has a prevalence of 6.4% in adults aged 50-79 and is strongly associated with coronary heart disease and peripheral arterial disease, warranting follow-up duplex scans in high-risk patients.
The aims of this epidemiological population-based cohort study were to examine the prevalence and outcomes of asymptomatic carotid stenosis (ACS) detected by duplex scanning and its relations to other vascular risk factors. A total of 500 volunteers, 200 men and 300 women, without signs and symptoms of cerebrovascular disease, aged 50-79 years, were enrolled in the study. The prevalence of ACS of 50% or greater was 6.4%. Only severe carotid stenosis was detected in 0.4% of the subjects examined. Significant relationships between ACS and coronary heart disease (CHD) [odds ratio (OR)=8.00], peripheral arterial disease (PAD) (OR=3.66), cigarette smoking in men (OR=4.39) and obesity in women (OR=0.31) were found. The biennial incidence rate of cerebral ischaemic events was 9.4%. A progression of ACS was revealed in 14% and a regression in 6.25% of the subjects. The patients with progressing ACS to more than 70% diameter reduction reached the end-points. Follow-up with repeated duplex scans in patients with advancing ACS of 50% or greater, especially smokers with CHD and PAD, is recommended.
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Mineva et al. (2002) conducted a cohort in Asymptomatic carotid stenosis (n=500). Asymptomatic carotid stenosis (exposure) was evaluated on Prevalence of asymptomatic carotid stenosis ≥50%. Asymptomatic carotid stenosis ≥50% had a prevalence of 6.4% in a population-based cohort, was strongly associated with coronary heart disease (OR 8.00), and had a 9.4% biennial ischemic event rate.
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