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Ultrasound‐Guided Iodine‐125 Seed Implantation for Cervical Metastatic Lymph Nodes: An Analysis of Efficacy and Safety

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Retrospective analysis shows effective local tumor control in patients with metastatic cervical lymph nodes, indicating a promising treatment option.

This study evaluates the efficacy and safety of ultrasound-guided iodine-125 seed implantation for treating metastatic cervical lymph nodes.
Retrospective analysis of 29 patients with 53 metastatic lymph nodes.
Iodine-125 seeds were implanted under ultrasound guidance based on pre-planned dose distribution.
Treatment response assessed with contrast-enhanced CT according to RECIST 1.1 criteria.
Local tumor control rates at 3, 6, and 12 months were 90.5%, 91.1%, and 75.9%, respectively.
1-year overall survival rate was 55.2%, and 2-year was 37.9%, observed over a mean follow-up of 15 months.
Only one case (3.4%) of skin injury was noted, with other adverse events being minor and manageable.

Li et al. (2026) studied this question.

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Retrospective analysis shows effective local tumor control in patients with metastatic cervical lymph nodes, indicating a promising treatment option.