Key result
Primary PCI during COVID-19 linked to higher TIMI frame counts and ~6-fold higher in-hospital mortality.
Why the study?
Data regarding organizational arrangements such as defining COVID-free heart centers during the first waves of COVID-19 is scarce.
Does the COVID-19 pandemic lockdown period impact angiographic endpoints and clinical outcomes in STEMI patients undergoing primary PCI at a COVID-free center?
Observational (n=125)
No
Does the COVID-19 pandemic lockdown period impact angiographic endpoints and clinical outcomes in STEMI patients undergoing primary PCI at a COVID-free center?
Despite reorganization as a COVID-free center, STEMI patients during the pandemic lockdown experienced significant pre-hospital delays, worse angiographic flow, and higher in-hospital mortality.
Pandemic-era STEMI patients had worse angiographic and mortality outcomes despite COVID-free centers; hypothesis-generating for pre-hospital delays and requires prospective confirmation.
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Serhan Özyıldırım (2023) conducted an observational in ST-Segment Elevation Myocardial Infarction (STEMI) (n=125). Primary percutaneous coronary intervention during COVID-19 pandemic vs. Primary percutaneous coronary intervention during pre-pandemic period (2019) was evaluated on Corrected TIMI frame count (cTFC) (p=<0.001). Primary percutaneous coronary intervention during the COVID-19 pandemic was associated with significantly higher corrected TIMI frame counts (32.9 vs. 27.3) and increased in-hospital mortality (11.4% vs. 1.8%) compared to the pre-pandemic period.
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