Key result
Morning hypertension significantly increased the risk of stroke compared to normotension (RH 2.66; 95% CI 1.64-4.33), particularly among individuals taking antihypertensive medication.
Why the study?
Do morning versus evening home blood pressure values differentially predict stroke incidence in adults ≥40 years?
Population
1766 subjects (≥40 years) in the Ohasama study
Comparison
Home blood pressure measurement in the morning vs Home blood pressure measurement in the evening…
Design
Cohort
Follow-up
average of 11 years
Authors
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Morning hypertension may flag elevated stroke risk in treated adults; extends home BP prognostic data but leaves causal benefit open.
Cohort (n=1,766)
Do morning versus evening home blood pressure values differentially predict stroke incidence in adults ≥40 years?
Effect estimate: RH 2.66 (95% CI 1.64-4.33)
Morning and evening home blood pressure provide equally useful prognostic information for stroke risk, but morning hypertension is a particularly strong predictor, especially in patients taking antihypertensive medication.
Asayama et al. (2006) conducted a cohort in Hypertension (n=1,766). Morning hypertension vs. Normotension was evaluated on Stroke incidence (RH 2.66, 95% CI 1.64-4.33). Morning hypertension significantly increased the risk of stroke compared to normotension (RH 2.66; 95% CI 1.64-4.33), particularly among individuals taking antihypertensive medication.
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