Key result
Overnight and morning urine collections predicted 24-hour microalbuminuria with 90% sensitivity and 88% specificity, demonstrating they are reliable alternatives for diagnosis.
Why the study?
Do overnight and morning urine collections accurately predict 24-hour microalbuminuria in patients with insulin-dependent diabetes mellitus?
Population
54 patients aged 17 to 62 years with insulin-dependent diabetes mellitus with a mean duration of 15 years
Comparison
Overnight and morning urine collections vs 24-hour urine collection
Design
Cross-sectional
Authors
Loading...
May ease microalbuminuria screening in diabetes; leaves open need for prospective validation before changing practice.
Cross-Sectional (n=54)
Do overnight and morning urine collections accurately predict 24-hour microalbuminuria in patients with insulin-dependent diabetes mellitus?
Overnight and morning urine collections, particularly when using the albumin to creatinine ratio, are reliable alternatives to 24-hour urine collection for diagnosing microalbuminuria in insulin-dependent diabetics.
Eshøj et al. (1987) conducted a cross-sectional in Insulin-dependent diabetes mellitus (n=54). Overnight and morning urine collections vs. 24-hour urine collection was evaluated on Ability to predict a 24-hour albumin excretion rate within the microalbuminuric range (20-200 micrograms/min). Overnight and morning urine collections predicted 24-hour microalbuminuria with 90% sensitivity and 88% specificity, demonstrating they are reliable alternatives for diagnosis.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: