What question did this study set out to answer?

To assess the population prevalence of microalbuminuria in diabetic patients and evaluate the diagnostic performance of three practical urine screening tests.

May 6, 1988Diabetic Medicine

Microalbuminuria in Diabetes: A Population Study of the Prevalence and an Assessment of Three Screening Tests

View Full Paper

Ask AI

Bookmark

Authors

WGW. GatlingPoole Hospital CKC KnightUniversity of London MMMark MulleeUniversity of Southampton

Discussion

Member takes

Implication

Population study reveals high microalbuminuria rates in diabetes and identifies overnight albumin-to-creatinine ratio as the optimal screen, indicating improved early kidney damage detection.

Key Points

To assess the population prevalence of microalbuminuria in diabetic patients and evaluate the diagnostic performance of three practical urine screening tests.
Reviewed 842 diabetic patients from 40 general practices, screening midstream urine samples for bacterial infection and overt proteinuria.
Assessed timed overnight urine collections for urinary albumin excretion rate (AER) alongside random and overnight urine albumin/creatinine ratios (Alb/Creat).
Microalbuminuria was detected in 133 of 450 patients (30%), with 31 patients (7%) having an AER greater than 30 µg/min.
Elevated random Alb/Creat occurred in 204 of 532 patients (38%) and correlated significantly with AER (r = 0.32, p < 0.001).
An overnight Alb/Creat threshold greater than 2.0 mg/mmol provided the optimal screening performance for predicting AER > 30 µg/min, with 96% sensitivity and 99.7% specificity.

Cite This Study

Gatling et al. (1988) studied this question.

synapsesocial.com/papers/6a80d5d266a8e49bcb4d54ca https://doi.org/10.1111/j.1464-5491.1988.tb01002.x

View Full Paper

Ask AI

Bookmark

Implication

Population study reveals high microalbuminuria rates in diabetes and identifies overnight albumin-to-creatinine ratio as the optimal screen, indicating improved early kidney damage detection.

Microalbuminuria in Diabetes: A Population Study of the Prevalence and an Assessment of Three Screening Tests

Discussion

Member takes

Implication

Key Points

Cite This Study

Microalbuminuria in Diabetes: A Population Study of the Prevalence and an Assessment of Three Screening Tests

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider