Key result
Serum HDL-C levels were significantly lower in subjects with major depression compared to normal controls, and in depressed men with a history of serious suicidal attempts.
Why the study?
Is major depression and suicidal behavior associated with lower serum HDL-C and immune/inflammatory markers?
Case-Control (n=64)
Is major depression and suicidal behavior associated with lower serum HDL-C and immune/inflammatory markers?
Major depression and suicidal behavior in men are associated with lower serum HDL-C levels, which correlate with immune-inflammatory markers and are not altered by short-term antidepressant treatment.
No takes yet. Share an insight, caveat, or question.
Lower HDL-C may mark depression and suicidality in men; leaves open causal links to immune-inflammatory pathways pending prospective studies.
Maes et al. (1997) conducted a case-control in Major depression (n=64). Antidepressants vs. Normal controls was evaluated on Serum HDL-C levels. Serum HDL-C levels were significantly lower in subjects with major depression compared to normal controls, and in depressed men with a history of serious suicidal attempts.
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