Key result
Selective atrioventricular nodal vagal stimulation consistently slowed ventricular rate by an average of 45 bpm over 5 weeks in dogs with induced atrial fibrillation.
Why the study?
Does selective atrioventricular nodal vagal stimulation reduce ventricular rate during atrial fibrillation in chronically instrumented dogs?
Population
18 chronically instrumented dogs with induced atrial fibrillation
Design
Preclinical
Follow-up
at least 5 weeks
Authors
Loading...
Extends acute vagal stimulation findings to chronic canine AF; leaves translation to human rate control open.
Does selective atrioventricular nodal vagal stimulation reduce ventricular rate during atrial fibrillation in chronically instrumented dogs?
Chronic selective atrioventricular nodal vagal stimulation safely and effectively reduces ventricular rate and improves cardiac indices during atrial fibrillation in a canine model.
Zhang et al. (2005) studied Atrial fibrillation (n=18). Selective atrioventricular nodal vagal stimulation (AVN-VS) was evaluated on Ventricular rate slowing. Selective atrioventricular nodal vagal stimulation consistently slowed ventricular rate by an average of 45 bpm over 5 weeks in dogs with induced atrial fibrillation.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: