Key result
Blood pressure control is a proven intervention to prevent progression of diabetic nephropathy and reduce cardiovascular events, with optimal targets and drug classes reviewed.
Why the study?
Does blood pressure control prevent progression of diabetic nephropathy and reduce cardiovascular events in patients with diabetes mellitus?
Does blood pressure control prevent progression of diabetic nephropathy and reduce cardiovascular events in patients with diabetes mellitus?
This review addresses optimal blood pressure targets, drug class advantages, and initiation timing for antihypertensive therapy in patients with diabetic nephropathy.
Supports BP control benefits in diabetic nephropathy; leaves open optimal targets and agents for prospective trials.
Epidemiologic studies show a worldwide diabetic epidemic. Diabetes mellitus is associated with a reduced life span due to macro vascular and micro vascular complications. Thus, diabetic nephropathy, which is the major cause of morbidity and mortality for patients with either type 1 diabetes mellitus or type 2 diabetes mellitus, is a public health care problem. Blood pressure control is a proven intervention to prevent progression of diabetic nephropathy and to reduce cardiovascular events in patients with diabetes mellitus. Establishment of optimal blood pressure targets, advantages of one class of drugs over another as well as time of initiation of antihypertensive therapy are those important questions that appear before every doctor. This review addresses these issues.
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Oleksandra Tkachenko (2014) conducted a review in Diabetic nephropathy. Blood pressure control was evaluated. Blood pressure control is a proven intervention to prevent progression of diabetic nephropathy and reduce cardiovascular events, with optimal targets and drug classes reviewed.
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