Key result
Primary percutaneous coronary intervention in a 61-year-old man with acute myocardial infarction and essential thrombocythemia resulted in massive in-stent thrombi formation.
Case Report (n=1)
In patients with essential thrombocythemia presenting with AMI, primary PCI carries an increased risk of in-stent thrombus formation, necessitating careful imaging-guided revascularization and aggressive antithrombotic therapy.
May warrant caution during PCI in essential thrombocythemia; hypothesis-generating for optimal antithrombotic strategies.
A 61-year-old man with essential thrombocythemia (ET) presented with acute myocardial infarction (AMI) and underwent primary percutaneous coronary intervention. After stent deployment from the left main (LM) to the left anterior descending artery, intravascular ultrasound revealed thrombi formation in the whole stent. Two days later, optical frequency domain imaging confirmed stent malapposition and thrombi remaining in only the LM. The stent malapposition and ET might have contributed to this phenomenon. He underwent an additional stent expansion and aggressive anti-thrombotic regimen. AMI complicated with ET carries increased risks of in-stent thrombi formation and requires careful revascularization and aggressive pharmacotherapy.
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Shoji et al. (2019) conducted a case report in Acute myocardial infarction complicated with essential thrombocythemia (n=1). Primary percutaneous coronary intervention was evaluated. Primary percutaneous coronary intervention in a 61-year-old man with acute myocardial infarction and essential thrombocythemia resulted in massive in-stent thrombi formation.
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