Key result
Age (beta=0.238), ambulatory pulse pressure (beta=0.130), smoking (beta=0.125), and LDL cholesterol (beta=0.125) were strongly associated with increased carotid intima-media thickness (P<0.0001).
Population
1224 Eastern Finnish men aged 42, 48, 54 or 60 years from the Kuopio Ischaemic Heart Disease Risk Factor Study
Design
Cross-sectional
Authors
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These associations should not yet change practice; extends observational consensus on vascular risks for subclinical atherosclerosis.
Cross-Sectional (n=1,224)
p-value: p=<0.0001
Systolic blood pressure, smoking, and serum LDL cholesterol are major risk factors for increased carotid intima-media thickness in middle-aged men.
Salonen et al. (1991) conducted a cross-sectional in Carotid intima-media thickness (n=1,224). Cardiovascular risk factors was evaluated on Maximal intima-media thickness of common carotid arteries (p=<0.0001). Age (beta=0.238), ambulatory pulse pressure (beta=0.130), smoking (beta=0.125), and LDL cholesterol (beta=0.125) were strongly associated with increased carotid intima-media thickness (P<0.0001).
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