Key result
In patients with severe right atrial conduction delay, continuous pacing at the inter-atrial septum was superior to right atrial appendage pacing for reducing AF recurrences.
Why the study?
Does pacing in the inter-atrial septum reduce atrial fibrillation recurrences compared to right atrial appendage pacing in patients with sinus node dysfunction and atrial fibrillation?
Population
42 patients with sinus node dysfunction (SND) and atrial fibrillation (AF), mean age 72 +/- 7 years, 15 male.
Comparison
Pacing in the inter-atrial septum with pacing… vs Pacing in the right atrial appendage with pacing…
Design
RCT, randomized to RAA/IAS pacing and algorithms ON/OFF
Authors
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Supports septal over appendage pacing in severe conduction delay; extends site-specific atrial pacing strategies for AF prevention.
RCT (n=42)
Randomized
Does pacing in the inter-atrial septum reduce atrial fibrillation recurrences compared to right atrial appendage pacing in patients with sinus node dysfunction and atrial fibrillation?
Absolute Event Rate: 0.06% vs 1.52%
In patients with sinus node dysfunction and severe right atrial conduction delay, continuous pacing at the inter-atrial septum is superior to the right atrial appendage for reducing atrial fibrillation recurrences.
Verlato et al. (2007) conducted an RCT in Sinus node dysfunction and atrial fibrillation (n=42). Inter-atrial septum (IAS) pacing vs. Right atrial appendage (RAA) pacing was evaluated on AF recurrences (episodes of AF/day). In patients with severe right atrial conduction delay, continuous pacing at the inter-atrial septum was superior to right atrial appendage pacing for reducing AF recurrences.
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