Key result
Right atrial overdrive pacing significantly reduced the median number of symptomatic paroxysmal atrial fibrillation episodes per week compared to no pacing (0.88 vs 2.02; P=0.001).
Why the study?
Does right atrial overdrive pacing reduce the number of symptomatic episodes of paroxysmal atrial fibrillation in patients without bradyarrhythmias?
Population
42 patients with frequent, symptomatic, and drug-refractory paroxysmal atrial fibrillation without…
Comparison
Right atrial AAI pacing at 10-19 beats/min above… vs No pacing (OAO mode) for 4-12 weeks.
Design
RCT, Programmed in random order (crossover design)
Follow-up
4-12 weeks per crossover period
Authors
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Right atrial overdrive pacing reduces symptomatic paroxysmal AF episodes; extends pacing indications to patients without bradyarrhythmias.
RCT (n=42)
Randomized crossover
Does right atrial overdrive pacing reduce the number of symptomatic episodes of paroxysmal atrial fibrillation in patients without bradyarrhythmias?
Absolute Event Rate: 0.88% vs 2.02%
p-value: p=0.001
Right atrial overdrive pacing significantly reduces the frequency of symptomatic paroxysmal atrial fibrillation episodes in patients without bradyarrhythmias.
WIBERG et al. (2003) conducted an RCT in Symptomatic paroxysmal atrial fibrillation (PAF) (n=42). Right atrial overdrive pacing vs. No pacing (OAO mode) was evaluated on Number of symptomatic episodes of PAF (>30-second duration) per week (p=0.001). Right atrial overdrive pacing significantly reduced the median number of symptomatic paroxysmal atrial fibrillation episodes per week compared to no pacing (0.88 vs 2.02; P=0.001).
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