Key result
This review highlights that chronic fatigue is associated with autonomic nerve dysfunction, sleep-rhythm disorders, and neural dysfunction in the central autonomic network.
Chronic fatigue syndrome involves complex interactions between autonomic dysfunction, sleep-rhythm disorders, and central nervous system alterations, suggesting potential new therapeutic targets.
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Hypothesis-generating for autonomic/sleep interventions in chronic fatigue; prospective trials needed before clinical adoption.
Tanaka et al. (2015) conducted a review in Fatigue and Chronic Fatigue Syndrome. This review highlights that chronic fatigue is associated with autonomic nerve dysfunction, sleep-rhythm disorders, and neural dysfunction in the central autonomic network.
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