Key result
A 30-minute fatigue-inducing mental task significantly increased subjective fatigue (VAS 21 to 47, P<0.001) and sympathetic nerve activity (%LF 38 to 48, P=0.035) in healthy volunteers.
Why the study?
Does a fatigue-inducing mental task alter autonomic nerve activities in healthy volunteers?
Population
19 healthy volunteers with no history of medical illness, weighing ≥ 40 kg.
Comparison
2-back test for 30 minutes as a fatigue-inducing… vs Baseline.
Design
Cross-sectional
Follow-up
Immediate (before and after 30-minute task)
Authors
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Mental fatigue may shift autonomic balance in healthy adults; hypothesis-generating for links to daily fatigue or CV risk.
Cross-Sectional (n=19)
No
Does a fatigue-inducing mental task alter autonomic nerve activities in healthy volunteers?
Absolute Event Rate: 47% vs 21%
p-value: p=< 0.001
Acute mental fatigue induces increased sympathetic and decreased parasympathetic nerve activities in healthy volunteers, which correlates with daily fatigue levels.
Tanaka et al. (2011) conducted a cross-sectional in Healthy volunteers (n=19). Fatigue-inducing mental task (2-back test) vs. Baseline (before task) was evaluated on Subjective level of fatigue (Visual Analogue Scale) (p=< 0.001). A 30-minute fatigue-inducing mental task significantly increased subjective fatigue (VAS 21 to 47, P<0.001) and sympathetic nerve activity (%LF 38 to 48, P=0.035) in healthy volunteers.
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