Why the study?
Does sodium intake modification alter the renin-aldosterone and blood pressure changes associated with a moderately low energy diet in middle-aged, moderately obese men with untreated mild hypertension?
Does sodium intake modification alter the renin-aldosterone and blood pressure changes associated with a moderately low energy diet in middle-aged, moderately obese men with untreated mild hypertension?
The hypotensive response to combined moderate energy and sodium reduction in obese hypertensive men is not mediated by changes in the renin-aldosterone system.
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Combined energy-sodium restriction may lower BP independently of renin-aldosterone changes; leaves open mechanisms and generalizability beyond small cohorts.
Fagerberg et al. (1985) studied this question.
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