Key result
Recent bleeding in patients with atrial fibrillation was associated with a higher likelihood of warfarin discontinuation compared to those without recent bleeding (RR 1.35; 95% CI 1.16-1.58).
Why the study?
What are the risk factors for warfarin discontinuation and bleeding in patients with atrial fibrillation?
Cohort (n=7,971)
What are the risk factors for warfarin discontinuation and bleeding in patients with atrial fibrillation?
Effect estimate: RR 1.35 (95% CI 1.16-1.58)
Absolute Event Rate: 61.8% vs 51.3%
Recent bleeding, older age, and frequent hospitalizations are significant risk factors for warfarin discontinuation in patients with atrial fibrillation.
No takes yet. Share an insight, caveat, or question.
Bleeding may prompt warfarin discontinuation in AF; leaves open whether targeted prevention improves long-term persistence.
Suh et al. (2013) conducted a cohort in Atrial fibrillation (n=7,971). Warfarin vs. No recent bleeding was evaluated on Warfarin discontinuation (RR 1.35, 95% CI 1.16-1.58). Recent bleeding in patients with atrial fibrillation was associated with a higher likelihood of warfarin discontinuation compared to those without recent bleeding (RR 1.35; 95% CI 1.16-1.58).
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