What does this research mean for the field?

Between 1971 and 1975 in the United States, non-polio enterovirus infections were highly seasonal, occurred more frequently in males, and demonstrated a decreasing incidence and potentially decreasing severity with advancing age across a variety of clinical presentations. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To evaluate national surveillance data on non-polio enterovirus isolations to identify seasonal patterns, demographic distributions, and associated clinical manifestations.

January 1, 1979International Journal of Epidemiology

Non-Polio Enterovirus Disease in the United States, 1971–1975

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Population

7,075 individuals with non-polio enterovirus isolations reported to the Center for Disease Control in the…

Design

Cross-sectional

Authors

DMDavid M. MorensUniversity of Chester RZRonald M. Zweighaft JBJohn M. BryanNorthwestern University

Discussion

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Implication

Supports seasonal surveillance planning; leaves open whether patterns persist in contemporary populations.

Key Points

To evaluate national surveillance data on non-polio enterovirus isolations to identify seasonal patterns, demographic distributions, and associated clinical manifestations.
Analyzed 5-year nationwide surveillance reports submitted to the Centers for Disease Control on non-polio enterovirus isolations (1971–1975, N=7,075).
Evaluated isolation distribution across months, age categories, biological sex, and reported clinical disease categories.
A total of 7,075 enterovirus isolations were documented, with 90% occurring during the 7-month window from May through November.
Enterovirus isolations occurred more frequently in males than females across every age group for all 5 years, with isolation incidence declining as age increased.
Identified clinical diagnoses included aseptic meningitis, encephalitis, upper and lower respiratory disease, gastroenteritis, exanthem, enanthem, and non-specific febrile illness, with an inverse relationship suggested between age and disease severity.

Structured PICO

Population

7,075 individuals with non-polio enterovirus isolations reported to the Center for Disease Control in the United States between 1971 and 1975.

Outcome

Incidence, seasonality, demographics, and clinical diagnoses of non-polio enterovirus isolations

Non-polio enterovirus infections in the US from 1971-1975 showed strong seasonality and male predominance, with severity inversely related to age.

Cite This Study

Morens et al. (1979) studied this question.

synapsesocial.com/papers/6a16ef62c7240d1a707bcd20 https://doi.org/10.1093/ije/8.1.49

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Non-Polio Enterovirus Disease in the United States, 1971–1975

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Non-Polio Enterovirus Disease in the United States, 1971–1975

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Also Consider