Rate of Intraoperative Crystalloid Administration During Thoracic Surgery Is Causal in Reducing Postoperative Hospital Length of Stay

Figures

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  Figure 1.. Bivariate fit of the role of intraoperative crystalloid administration (mL/kg/hr) on postoperative hospital length of stay following thoracic surgery in 222 consecutive patients. Postoperative hospital length of stay = 9.7 – 0.27 × intraoperative crystalloid administration rate + 0.004 × (intraoperative crystalloid administration rate – 12.06)2; F-ratio=7.6, P=0.0006. P values <0.01 are statistically significant.

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  Figure 2.. Logistic fit of the role of intraoperative crystalloid administration (mL/kg/hr) on the incidence of common postoperative surgical adverse events (AEs) following thoracic surgery in 222 consecutive patients. The blue lines are the percent incidence fit of the dose-response relationship to surgical AEs. P values <0.01 are statistically significant. (A) Unplanned surgical intensive care unit (SICU) admission: chi-square=3.8, P=0.0527; (B) Reoperation: chi-square=5.8, P=0.0161; (C) Wound infection: chi-square=0.6, P=0.4528; (D) Ileus requiring total parenteral nutrition (TPN): chi-square=0.002, P=0.9647; (E) Total surgical AEs: chi-square=9.1, P=0.0026.

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  Figure 3.. Logistic fit of the role of intraoperative crystalloid administration (mL/kg/hr) on the incidence of common postoperative cardiovascular adverse events (AEs) following thoracic surgery in 222 consecutive patients. The blue lines are the percent incidence fit of the dose-response relationship to cardiovascular AEs. P values <0.01 are statistically significant. (A) Postoperative nonsinus dysrhythmias: chi-square=5.2, P=0.0229; (B) Postoperative hypertension: chi-square=2.2, P=0.1381; (C) Postoperative hypotension requiring therapy: chi-square=0.18, P=0.6721; (D) Total cardiovascular AEs: chi-square=4.0, P=0.0446.

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  Figure 4.. Logistic fit of the role of intraoperative crystalloid administration (mL/kg/hr) on the incidence of common postoperative pulmonary adverse events (AEs) following thoracic surgery in 222 consecutive patients. The blue lines are the percent incidence fit of the dose-response relationship to pulmonary AEs. P values <0.01 are statistically significant. (A) Pneumonia: chi-square=0.9, P=0.3412; (B) Respiratory failure requiring orotracheal reintubation: chi-square=4.8, P=0.0281; (C) Pulmonary embolus: chi-square=0.85, P=0.3559; (D) Pneumothorax: chi-square=4.9, P=0.0276; (E) Total pulmonary AEs: chi-square=5.9, P=0.0155.

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  Figure 5.. Logistic fit of the role of intraoperative crystalloid administration (mL/kg/hr) on the incidence of common postoperative renal adverse events (AEs) following thoracic surgery in 222 consecutive patients. The blue lines are the percent incidence fit of the dose-response relationship to renal AEs. P values <0.01 are statistically significant. (A) Urinary tract infection: chi-square=2.5, P=0.1118; (B) New onset renal insufficiency: chi-square=7.5, P=0.0063; (C) Total renal AEs: chi-square=9.1, P=0.0025.

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  Figure 6.. Logistic fit of the role of intraoperative crystalloid administration (mL/kg/hr) on the incidence of common postoperative other adverse events (AEs) following thoracic surgery in 222 consecutive patients. The blue lines are the percent incidence fit of the dose-response relationship to other AEs. P values <0.01 are statistically significant. (A) Deep venous thrombosis: chi-square=0.002, P=0.9647; (B) Postoperative delirium: chi-square=4.1, P=0.0424; (C) Total other AEs: chi-square=3.6, P=0.0580.

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  Figure 7.. Logistic fit of the role of intraoperative crystalloid administration (mL/kg/hr) on the incidence of long-term adverse events (AEs) following thoracic surgery in 222 consecutive patients. The blue lines are the percent incidence fit of the dose-response relationship to long-term AEs. P values <0.01 are statistically significant. (A) Readmission in 30 days: chi-square=0.7, P=0.4104; (B) Long-term acute care (LTAC) placement: chi-square=1.2, P=0.2822; (C) Mortality: chi-square=0.1, P=0.8107; (D) Total long-term AEs: chi-square=0.5, P=0.4980.