Key result
Cyclic alternating pattern (CAP) during non-REM sleep was associated with significantly higher blood pressure and baroreflex sensitivity compared to non-CAP periods.
Observational (n=10)
Throughout the overnight sleep period, the arterial baroreflex acts to buffer surges of sympathetic activation during non-REM sleep by means of rapid changes in cardiac vagal circuits.
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Should not yet guide nocturnal BP management; leaves open CAP's causal role in hypertension.
Iellamo et al. (2004) conducted an observational in Healthy males (n=10). Sleep microstructure (cyclic alternating pattern) vs. Non-cyclic alternating pattern (non-CAP), REM sleep, and wakefulness was evaluated on Heart rate, blood pressure variability, and baroreflex sensitivity (BRS). Cyclic alternating pattern (CAP) during non-REM sleep was associated with significantly higher blood pressure and baroreflex sensitivity compared to non-CAP periods.
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