January 1, 2000Journal of Cardiovascular Pharmacology
Mechanisms and Clinical Implications of Blood Pressure Variability
Key result
Blood pressure variability over 24 hours correlates with and promotes hypertension-related target-organ damage, driven significantly by sympathetic neural factors.
Population
Patients with hypertension
Design
Review
Authors
Discussion
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Member takes
Implication
May inform hypertension risk stratification; leaves open whether sympathetic modulation reduces target-organ damage.
Structured PICO
P
Population
Patients with hypertension
24-hour blood pressure variability, driven partly by sympathetic neural factors, plays a clinically relevant role in promoting target-organ damage in hypertensive patients.
Cite This Study
Mancia et al. (2000) conducted a review in Hypertension. Blood pressure variability was evaluated on Target-organ damage. Blood pressure variability over 24 hours correlates with and promotes hypertension-related target-organ damage, driven significantly by sympathetic neural factors.