Key result
Adding GLS to TIMI score improves 12-month MACE prediction to an AUC of 0.81.
Why the study?
Accurately assessing prognosis is important in STEMI, and the predictive value of combining the TIMI risk score with GLS for MACE after PCI needed investigation.
Does combining the TIMI risk score with global longitudinal strain improve the prediction of major adverse cardiovascular events in STEMI patients after PCI?
Cohort (n=138)
No
Does combining the TIMI risk score with global longitudinal strain improve the prediction of major adverse cardiovascular events in STEMI patients after PCI?
Answers are grounded in this paper and cite their sources.
Combining global longitudinal strain with the TIMI risk score significantly improves the prediction of major adverse cardiovascular events in STEMI patients following PCI compared to the TIMI risk score alone.
PurposeAccurately assessing the predicting prognosis is important in ST-segment elevation myocardial infarction (STEMI). This study aimed to investigate the predictive value of the TIMI risk score combined with GLS for the occurrence of major adverse cardiovascular events (MACEs)in STEMI patients after percutaneous coronary intervention (PCI)MethodsAcute STEMI diagnosed between January 2019 to June 2021 were prospectively enrolled. GLS were performed to assess left ventricular dysfunction three days post-percutaneous coronary intervention (PCI). In a 12-month follow up, three prognostic models for MACE were established based on TIMI risk score alone, TIMI risk score + GLS, and TIMI risk score + GLS + clinical risk factors, respectively, and assessed for efficiency.ResultsA total of 138 patients were enrolled. According to the follow-up results, the incidence of MACE in the patients was 19.6% (27/138). Areas under the receiver operating characteristic (ROC) curves were 0.703, 0.810 and 0.815, respectively, in TIMI risk score alone, TIMI risk score + GLS, TIMI risk score + GLS + clinical risk factors, indicating a significantly higher value and more efficient assessment for TIMI risk score + GLS.ConclusionCompared with the TIMI risk score alone, TIMI risk score combined with GLS provides a more efficient assessment of risk for determining the prognosis of STEMI patients.
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Yang et al. (2021) conducted a cohort in ST-segment elevation myocardial infarction (STEMI) (n=138). TIMI risk score combined with Global Longitudinal Strain (GLS) vs. TIMI risk score alone was evaluated on Area under the ROC curve (AUC) for predicting major adverse cardiovascular events (MACE) (p=0.026). TIMI risk score combined with global longitudinal strain significantly improved the prediction of major adverse cardiac events at 12 months compared to TIMI risk score alone (AUC 0.810 vs 0.703).
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