Key result
Deep learning using raw PPG and demographics estimates average ABP pulse with ~9 mmHg error.
Why the study?
Cuff-based arterial blood pressure monitoring only yields systolic and diastolic values, lacking full pulse morphology assessment useful for diagnosing cardiovascular diseases.
Does a deep learning model using photoplethysmogram signals and demographic information accurately estimate arterial blood pressure morphology?
Does a deep learning model using photoplethysmogram signals and demographic information accurately estimate arterial blood pressure morphology?
A deep learning model using PPG signals and demographic information can estimate arterial blood pressure morphology with high correlation to actual ABP pulses, offering a potential cuff-free monitoring method.
Arterial blood pressure (ABP) is an important vital sign from which it can be extracted valuable information about the subject's health. After studying its morphology it is possible to diagnose cardiovascular diseases such as hypertension, so ABP routine control is recommended. The most common method of controlling ABP is the cuff-based method, from which it is obtained only the systolic and diastolic blood pressure (SBP and DBP, respectively). This paper proposes a cuff-free method to estimate the morphology of the average ABP pulse (ABPM¯) through a deep learning model based on a seq2seq architecture with attention mechanism. It only needs raw photoplethysmogram signals (PPG) from the finger and includes the capacity to integrate both categorical and continuous demographic information (DI). The experiments were performed on more than 1100 subjects from the MIMIC database for which their corresponding age and gender were consulted. Without allowing the use of data from the same subjects to train and test, the mean absolute errors (MAE) were 6.57 ± 0.20 and 14.39 ± 0.42 mmHg for DBP and SBP, respectively. For ABPM¯, R correlation coefficient and the MAE were 0.98 ± 0.001 and 8.89 ± 0.10 mmHg. In summary, this methodology is capable of transforming PPG into an ABP pulse, which obtains better results when DI of the subjects is used, potentially useful in times when wireless devices are becoming more popular.
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Aguirre et al. (2021) studied Blood pressure estimation (n=1,100). Deep learning model based on a seq2seq architecture with attention mechanism was evaluated on Mean absolute errors (MAE) for DBP, SBP, and average ABP pulse (ABPM¯). A deep learning model using raw photoplethysmogram signals and demographic information estimated average arterial blood pressure pulse morphology with a mean absolute error of 8.89 ± 0.10 mmHg.
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