Key result
Conception in spring and summer months (February and April through August) was associated with a higher prevalence of preeclampsia compared to January conceptions (PRs 1.14-1.19).
Why the study?
Does the month of conception affect the prevalence of preeclampsia in primiparous women?
Population
79,298 primiparous women in Washington State who delivered a singleton live infant from 1987 through 2001…
Comparison
Conception in February and April through August vs Conception in January (month of lowest prevalence)
Design
Cohort
Authors
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Does not support changing prenatal care by conception month; leaves open environmental contributions to preeclampsia etiology.
Observational (n=79,298)
Does the month of conception affect the prevalence of preeclampsia in primiparous women?
Effect estimate: PR 1.14-1.19
Absolute Event Rate: 8.9% vs 7.7%
Preeclampsia prevalence among primiparous women peaks for conceptions occurring in spring and summer, suggesting seasonal environmental exposures may contribute to its etiology.
Rudra et al. (2005) conducted an observational in Preeclampsia (n=79,298). Conception in spring and summer months vs. Conception in January was evaluated on Preeclampsia prevalence (PR 1.14-1.19). Conception in spring and summer months (February and April through August) was associated with a higher prevalence of preeclampsia compared to January conceptions (PRs 1.14-1.19).
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