Key result
The term 'essential hypertension' obscures complex, modifiable causes of elevated blood pressure like salt sensitivity and obesity, and should be replaced with mechanism-based classifications.
This perspective argues for abandoning the term 'essential hypertension' in favor of a mechanism-based classification that recognizes modifiable drivers like salt sensitivity and obesity to enable personalized medicine.
The Stanley Peart Essay Competition is an annual event run by the British and Irish Hypertension Society to encourage Early Career Researchers to continue the ethos of Sir Stanley Peart. Sir Stanley Peart was a clinician and clinical researcher who made a major contribution to our understanding of blood pressure regulation. He was the first to demonstrate the release of noradrenaline in response to sympathetic nerve stimulation. He was also the first to purify, and determine the structure of, angiotensin and he later isolated the enzyme, renin, and carried out many important investigations of the factors controlling its release in the body. This year, the essay topic was "Is Essential Hypertension really Primary or Essential?". In her prize-winning essay, Victoria Dahmen questions the continued use of the term "essential hypertension" suggesting that it may obscure the complex and often modifiable factors contributing to elevated blood pressure. By exploring the roles of salt sensitivity, obesity, and their physiological interplay, her essay calls for a more nuanced, mechanism-based classification of hypertension. Such a shift, she argues, will facilitate clinicians to deliver personalised medicine by aligning medical language with modern scientific understanding.
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Victoria D. Dahmen (2025) conducted an editorial in Hypertension. The term 'essential hypertension' obscures complex, modifiable causes of elevated blood pressure like salt sensitivity and obesity, and should be replaced with mechanism-based classifications.
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