Key result
Left atrial diameter ≥55 mm in patients with mitral regurgitation due to flail leaflets independently predicted overall mortality under medical treatment (HR 3.67; 95% CI 1.95-6.88).
Why the study?
Does left atrial diameter ≥55 mm predict mortality in patients with organic mitral regurgitation due to flail leaflets?
Population
788 patients with organic mitral regurgitation due to flail leaflets in sinus rhythm, mean age 64±12 years…
Comparison
Left atrial diameter ≥55 mm vs Left atrial diameter <55 mm
Design
Cohort
Follow-up
up to 8 years
Authors
Loading...
In patients with mitral regurgitation due to flail leaflets, a left atrial diameter ≥55 mm is a strong independent predictor of mortality under medical treatment, suggesting it should be considered in risk stratification and timing of surgery.
Cohort (n=788)
Yes
Does left atrial diameter ≥55 mm predict mortality in patients with organic mitral regurgitation due to flail leaflets?
Effect estimate: HR 3.67 (95% CI 1.95-6.88)
p-value: p=<0.001
In patients with mitral regurgitation due to flail leaflets, a left atrial diameter ≥55 mm is a strong independent predictor of mortality under medical treatment, suggesting it should be considered in risk stratification and timing of surgery.
Ruşinaru et al. (2011) conducted a cohort in Organic mitral regurgitation due to flail leaflets (n=788). Left atrial diameter ≥55 mm vs. Left atrial diameter <55 mm was evaluated on Overall mortality under medical treatment (HR 3.67, 95% CI 1.95-6.88, p=<0.001). Left atrial diameter ≥55 mm in patients with mitral regurgitation due to flail leaflets independently predicted overall mortality under medical treatment (HR 3.67; 95% CI 1.95-6.88).