Key result
Japan NCVC criteria yield ~89% diagnostic accuracy for identifying coronary embolism in AMI.
Why the study?
Coronary embolism is a rare cause of acute myocardial infarction, and the Japan NCVC criteria for its diagnosis had not been verified or widely accepted.
Observational (n=18)
No
The Japan NCVC criteria are a useful and highly accurate (88.9%) diagnostic tool for coronary embolism in AMI, for which thrombus aspiration is the preferred initial treatment.
Hypothesis-generating for NCVC criteria in AMI embolism; prospective validation needed before clinical adoption.
BACKGROUND: Coronary embolism (CE) is rare and is an unusual cause of acute myocardial infarction (AMI). Japan NCVC criteria of CE were the first criteria that did not be verified and accepted. METHODS: We collected all the CE patients in our hospital between 2015 and 2021, analyzed the characters, diagnosis, and treatment, and confirmed the value of Japan NCVC criteria. RESULTS: Eighteen AMI patients diagnosed with CE were enrolled. Seventeen patients (94.4%) were given PCI treatments. Six patients (33.3%) had artificial heart valves, and three (16.7%) had mechanical valves. Eleven patients (61.1%) had atrial fibrillation (AF), one (5.6%) had hypertrophic cardiomyopathy, and two (11.1%) had hypercoagulable state. 68.8% of patients had insufficient anticoagulation in this study. Seven patients (38.9%) fulfilled the criteria for definite CE, and nine (50%) were classified as probable CE. The other two patients (11.1%) did not fulfill the criteria of CE with distal coronary artery embolism and one criterion of Japan NCVC criteria. The diagnosis accuracy rate of Japan NCVC criteria was 88.9%. Thrombus aspiration was the first-line treatment used in 14 patients (77.8%) and performed in 9 vessels (47.4%) as the only treatment method. CONCLUSIONS: CE is rare in AMI, and AF is the most critical cause which should draw our attention. The Japan NCVC criteria were a helpful diagnostic tool for CE with high accuracy, but the distal coronary artery embolism with moderate atherosclerosis might be overlooked. Thrombus aspiration was the preferred treatment to remove thrombus and restore coronary flow to improve prognosis.
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Chang et al. (2025) conducted an observational in Coronary embolism resulting in acute myocardial infarction (n=18). Japan NCVC diagnostic criteria and percutaneous coronary intervention was evaluated on Diagnostic accuracy rate of Japan NCVC criteria. The Japan NCVC criteria demonstrated an 88.9% diagnostic accuracy rate for identifying coronary embolism in patients with acute myocardial infarction.
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