What question did this study set out to answer?

To synthesize the current state of knowledge regarding coronary artery embolism as an underdiagnosed cause of acute coronary syndrome.

July 19, 2022Trends in Cardiovascular MedicineOpen Access

Coronary artery embolism and acute coronary syndrome: A critical appraisal of existing data

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Why the study?

Coronary artery embolism is an underrecognized cause of acute coronary syndrome, and the authors sought to determine the current state of knowledge on this condition.

Population

Articles on acute coronary syndrome related to coronary artery embolism published between 1 January 1990 and 31 December 2021

Design

Comprehensive structured literature search

Authors

AMAntoine MoninUniversité de Bourgogne RDRomain DidierInserm TLThibault LeclercqCentre Georges François Leclerc

Discussion

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Implication

CE prevalence in MI may be underestimated; leaves open need for standardized diagnostics and prospective outcome data.

Key Points

To synthesize the current state of knowledge regarding coronary artery embolism as an underdiagnosed cause of acute coronary syndrome.
Conducted a structured literature search of the MEDLINE database for articles published between January 1, 1990, and December 31, 2021.
Synthesized evidence from published case series on diagnostic classifications, etiologies, concurrent systemic emboli, and clinical outcomes.
Coronary artery embolism accounts for approximately 5% of myocardial infarctions, with primary identified etiologies including atrial fibrillation (28.3% to 73%), cardiomyopathy (9.4% to 25%), and malignancy (9.6% to 15.1%), while 26.3% have no identifiable cause.
Simultaneous systemic embolization occurs in approximately 25% of cases, primarily targeting the brain (67%), limbs (25%), kidneys (25%), and spleen (4%).

Structured PICO

Population

Patients with acute coronary syndrome (ACS) related to coronary artery embolism (CE)

Coronary artery embolism is a rare but significant non-atherosclerotic cause of acute coronary syndrome that requires systematic assessment for etiologies like atrial fibrillation and simultaneous systemic embolization.

Cite This Study

Monin et al. (2022) studied this question.

synapsesocial.com/papers/6a738da0427d94f6ee71b466 https://doi.org/10.1016/j.tcm.2022.07.004

Topics

Coronary artery disease Atrial fibrillation Persistent AF management

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Coronary artery embolism and acute coronary syndrome: A critical appraisal of existing data

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Coronary artery embolism and acute coronary syndrome: A critical appraisal of existing data

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

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Topics

Also Consider