Why the study?
Is nonalcoholic fatty liver disease associated with carotid stenosis or plaque in a community-based Chinese population?
Population
2,612 adults aged 40 years and older from a community-based population in Jidong of Tangshan city, China.
Comparison
Presence of nonalcoholic fatty liver disease… vs Absence of NAFLD
Design
Cross-sectional
Key result
Nonalcoholic fatty liver disease was significantly associated with a higher prevalence of carotid stenosis (OR 2.06) compared to individuals without the disease in a Chinese community population.
Authors
Loading...
Should not yet inform carotid screening or risk stratification; extends observational links in Chinese adults but leaves causality and outcomes open.
Cross-Sectional (n=2,612)
No
Is nonalcoholic fatty liver disease associated with carotid stenosis or plaque in a community-based Chinese population?
Effect estimate: OR 2.06 (95% CI 1.45-2.91)
Absolute Event Rate: 12.9% vs 4.6%
p-value: p=<0.01
NAFLD is independently associated with a twofold increased odds of carotid stenosis in a Chinese community-based population aged 40 and older.
Guo et al. (2018) conducted a cross-sectional in Nonalcoholic fatty liver disease and carotid artery disease (n=2,612). Nonalcoholic fatty liver disease (NAFLD) vs. Without NAFLD was evaluated on Carotid stenosis (OR 2.06, 95% CI 1.45-2.91, p=<0.01). Nonalcoholic fatty liver disease was significantly associated with a higher prevalence of carotid stenosis (OR 2.06) compared to individuals without the disease in a Chinese community population.