Key result
A right ventricular myocardial performance index <0.47 identified preserved right ventricular function, while echocardiographically determined ejection fraction did not correlate with MRI values.
Why the study?
Do echocardiography-derived right ventricular parameters correlate with MRI-derived ejection fraction in patients late after the Senning procedure?
Observational (n=44)
Do echocardiography-derived right ventricular parameters correlate with MRI-derived ejection fraction in patients late after the Senning procedure?
Effect estimate: r2 0.29 and 0.04
In patients late after the Senning procedure, echocardiographic ejection fraction and dP/dt do not correlate well with MRI-derived ejection fraction, though a right ventricular myocardial performance index <0.47 may indicate preserved right ventricular function.
Echo EF unreliable vs MRI for RV function post-Senning; hypothesis-generating for MPI <0.47 pending validation.
Deteriorating ventricular function is a major concern after the Senning operation. A Doppler-derived non-geometric measurement, the so-called myocardial performance index, has been described for use in adults and children. We aimed to assess the utility of this index as a method for quantification of right ventricular function in patients in the late follow-up of the Senning procedure, and to correlate the right ventricular ejection fraction and the first derivative of right ventricular pressure as derived using echocardiography with the ejection fraction determined using magnetic resonance imaging. We studied 44 patients within a mean postoperative period of 15.3 years. We calculated the right ventricular myocardial performance index by pulsed wave Doppler interrogation of tricuspid inflow and aortic outflow, the ejection fraction by Simpson's rule, and the first derivative of right ventricular pressure by continuous wave Doppler from tricuspid regurgitation. Mean values of right ventricular myocardial performance index, ejection fraction, and the first derivative of right ventricular pressure were 0.50, 39 percent and 1,398 millimetres of mercury per second, respectively. A cut-off value of 0.47 for the right ventricle myocardial performance index was determined, with a sensitivity of 75 percent and a specificity of 62.5 percent. We found no correlation between ejection fraction and the first derivative of right ventricular pressure as estimated by echocardiography and the ejection fraction as shown by magnetic resonance imaging (r2 equal to 0.29 and 0.04 respectively). We concluded, first, that patients with preserved right ventricular function had values for the right ventricular myocardial performance index lower than 0.47, and second, that ejection fraction and the first derivative of right ventricular pressure as determined echocardiographically did not correlate with values derived using magnetic resonance imaging.
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Morhy et al. (2005) conducted an observational in Late follow-up of the Senning procedure (n=44). Echocardiography (myocardial performance index, ejection fraction, dP/dt) vs. Magnetic resonance imaging was evaluated on Correlation of echocardiographic right ventricular ejection fraction and dP/dt with MRI-derived ejection fraction (r2 0.29 and 0.04). A right ventricular myocardial performance index <0.47 identified preserved right ventricular function, while echocardiographically determined ejection fraction did not correlate with MRI values.
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