Key result
A 100-km ultramarathon induced significantly higher increases in creatinine kinase, NT-proBNP, and C-reactive protein in marathoners with exercise-induced hypertension compared to normal marathoners (P<0.05).
Why the study?
Does a 100-km ultramarathon affect cardiac markers differently in exercise-induced-hypertensive marathoners compared to normal marathoners?
Observational (n=20)
Does a 100-km ultramarathon affect cardiac markers differently in exercise-induced-hypertensive marathoners compared to normal marathoners?
Exercise-induced-hypertensive marathoners experience higher myocardial stress and muscle damage during a 100-km ultramarathon compared to normal marathoners, though without overt myocardial damage.
This study aimed to investigate effects of a 100-km ultramarathon on cardiac markers of exercise-induced-hypertensive marathoners. 10 marathoners with exercise-induced hypertension and 10 normal marathoners participated in the study. Their blood samples were collected before starting, at 50 km, and after finishing the course (100 km). Creatinine kinase was more significantly increased in the exercise-induced-hypertensive group than in the normal group at 100 km (P<0.05). N-terminal pro-brain nutriuretic peptide was significantly increased in the exercise-induced-hypertensive group at 50 km and 10 km (P<0.05) which was significant being doubled compared to the normal group (P<0.05). Exercise-induced-hypertensive marathoners showed a significant triple-increase in C-Reactive protein at 100 km (P<0.05). In conclusion, although the exercise-induced-hypertensive runners did not have myocardial damage during the 100 km ultramarathon, they had higher myocardial stress and more damage in active muscles due to a bloodstream disability.
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Kim et al. (2012) conducted an observational in Exercise-induced hypertension (n=20). 100-km ultramarathon vs. Normal marathoners was evaluated on Cardiac markers (Creatinine kinase, NT-proBNP, CRP) (p=<0.05). A 100-km ultramarathon induced significantly higher increases in creatinine kinase, NT-proBNP, and C-reactive protein in marathoners with exercise-induced hypertension compared to normal marathoners (P<0.05).
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