Key result
Pharmacological treatment of acute, asymptomatic, in-hospital blood pressure elevations may have no benefit and could increase the risk of in-hospital and post-discharge complications.
Why the study?
While long-term community hypertension control reduces cardiovascular risk, the benefit of controlling acute blood pressure elevations in hospitalised patients is unclear.
Does pharmacological treatment of acute, asymptomatic blood pressure elevations in hospitalized patients improve outcomes?
Does pharmacological treatment of acute, asymptomatic blood pressure elevations in hospitalized patients improve outcomes?
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Acute, asymptomatic blood pressure elevations in hospitalized patients should not routinely be treated with antihypertensives, but rather followed up after discharge.
Long-term hypertension control in the community significantly reduces cardiovascular risk. However, the benefit of controlling acute elevations of blood pressure in hospitalised patients is unclear. In-hospital elevations of blood pressure are relatively common and might not reflect poorly controlled blood pressure before admission. The measurement of blood pressure in hospital patients significantly differs from the best practice recommended for primary care and outpatients. Recent observational studies suggest that the pharmacological treatment of acute, asymptomatic, in-hospital elevations of blood pressure may have no benefit. However, it may increase the risk of in-hospital and post-discharge complications. Pending the development of robust inpatient measurement protocols, acute blood pressure elevations in hospitalised patients should not routinely require antihypertensive treatment in the absence of symptoms or acute end-organ damage. Rather, such elevations should facilitate follow-up of blood pressure and other cardiovascular risk factors after discharge.
Mangoni et al. (2022) conducted a review in Acute, asymptomatic, in-hospital elevations of blood pressure. Pharmacological treatment vs. No routine antihypertensive treatment was evaluated. Pharmacological treatment of acute, asymptomatic, in-hospital blood pressure elevations may have no benefit and could increase the risk of in-hospital and post-discharge complications.