What does this research mean for the field?

Distinct patterns of matrix metalloproteinase (MMP) activation and loss of endogenous tissue inhibitor (TIMP) control drive left ventricular remodeling across different cardiac pathologies, presenting specific targets for therapeutic intervention. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

January 1, 2004AJP Heart and Circulatory Physiology

Extracellular protease activation and unraveling of the myocardial interstitium: critical steps toward clinical applications

View Full Paper

Ask AI

Bookmark

Key Points

Key points are not available for this paper at this time.

Design

Editorial

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

This editorial highlights the critical role of matrix metalloproteinases in myocardial extracellular matrix remodeling and left ventricular failure, suggesting them as potential therapeutic and prognostic targets.

Cite This Study

Chapman et al. (2004) studied this question.

synapsesocial.com/papers/6a17bb3ccf49e78c48b4633d https://doi.org/10.1152/ajpheart.00609.2003

Topics

Cardiomyopathy

View Full Paper

Ask AI

Bookmark

Extracellular protease activation and unraveling of the myocardial interstitium: critical steps toward clinical applications

Key Points

Discussion

Implication

Cite This Study

Topics

Extracellular protease activation and unraveling of the myocardial interstitium: critical steps toward clinical applications

Key Points

Discussion

Implication

Cite This Study

Also Consider

Topics

Also Consider