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Transforming growth factor beta-1 (TGF-beta 1) is dynamically regulated following acute myocardial infarction, characterized by an initial loss in infarcted tissue and subsequent marked upregulation at the infarct margins, indicating it plays a significant role in the cardiac response to injury. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

January 1, 1988Growth Factors

Transforming Growth Factor Beta-1 in Acute Myocardial Infarction in Rats

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Authors

NTNancy L. ThompsonUniversity of North Carolina at Chapel Hill FBFernando BazoberryNational Institutes of Health ESEdith SpeirUniversity of North Carolina at Chapel Hill

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Implication

TGF-β1 dynamics post-MI may inform repair strategies; extends RCT evidence on growth factors in cardiac injury.

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Thompson et al. (1988) studied this question.

synapsesocial.com/papers/6a17ce8d4f2b3115b013089b https://doi.org/10.3109/08977198809000251

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Transforming Growth Factor Beta-1 in Acute Myocardial Infarction in Rats

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Key Points

Cite This Study

Transforming Growth Factor Beta-1 in Acute Myocardial Infarction in Rats

Discussion

Member takes

Implication

Key Points

Cite This Study

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