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Case presentation demonstrates total knee arthroplasty improves pain and function in alkaptonuric patients, suggesting a viable treatment option.
Background: We present a patient with ochronotic arthropathy admitted to perform total knee arthroplasty (TKA) of the right knee. Case Presentation: The patient admitted to the orthopaedic department presented with pain in multiple joints, particularly affecting the knees, hips, and shoulders. Intervention: Preoperatively, the patient underwent meticulous preparation for the procedure in consultation with the anesthesiology team. During the surgery, we observed black bones and menisci in the joint. Outcome: The patient felt a massive relief after TKA. At 1-month follow-up, the patient reported a satisfying range of motion of the knee. Conclusions: Our findings suggest that TKA may represent an effective therapeutic option for patients with alkaptonuria and degenerative joint disease because it may provide substantial pain relief and improve joint function.
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Michalak et al. (2026) studied this question.
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