Key result
Weekend admission or discharge linked to ~36% higher in-hospital mortality versus weekday patterns in older adults.
Why the study?
The impact of the weekend effect on hospitalization outcomes remains debated.
Does a weekend-admission/discharge pattern affect mortality and readmission risks in older adults with emergency hospitalizations?
Cohort (n=3,447,877)
Yes
Does a weekend-admission/discharge pattern affect mortality and readmission risks in older adults with emergency hospitalizations?
Weekend admission or discharge is associated with higher in-hospital mortality but paradoxically lower 30-day post-discharge risks, highlighting complex systemic care integration challenges and selective discharge patterns.
Answers are grounded in this paper and cite their sources.
Weekend timing patterns may flag higher in-hospital mortality risk in older patients; leaves open causal effects and need for prospective studies.
The impact of the weekend effect on hospitalization outcomes remains debated. This study evaluated the “weekend effect” by defining two distinct patterns based on admission–discharge timing: “weekend-admission/discharge” (either admission or discharge occurring on weekends) and “weekday-admission-discharge” (both admission and discharge occurring on weekdays). Utilizing 3,447,877 emergency hospitalization spells among older patients in Hong Kong from 2012 to 2021, multivariable logistic regression with a random effect of hospital revealed that the weekend-admission/discharge pattern accounted for 42.5% of hospitalizations and was associated with significantly higher in-hospital mortality (5.0% vs. 3.8%; adjusted odds ratio [aOR] = 1.359, 95% CI: 1.344–1.373). Paradoxically, this pattern demonstrated minimally protective effects for post-discharge outcomes, with lower 30-day mortality (aOR = 0.963, 95% CI: 0.948–0.978) and reduced 30-day emergency readmission risk (aOR = 0.986, 95% CI: 0.979–0.992). Subgroup analyses confirmed consistent elevation of in-hospital mortality risk across all spell groups, while revealing substantial variations by length of stay, clinical specialty, and principal diagnosis. The protective post-discharge effects were predominantly observed among those with longer hospitalizations. These findings demonstrate a complex duality in weekend care outcomes and suggest that the weekend effect reflects systemic care integration challenges and selective discharge patterns rather than simple temporal variations in care quality. Future quality improvement initiatives should focus on enhancing care continuity and developing targeted approaches for high-risk clinical contexts. Meanwhile, more research is needed to elucidate the underlying mechanisms driving these paradoxical outcomes.
No takes yet. Share an insight, caveat, or question.
Yu et al. (2026) conducted a cohort in Emergency hospitalizations (n=3,447,877). Weekend-admission/discharge pattern vs. Weekday-admission-discharge pattern was evaluated on All-cause in-hospital mortality (aOR 1.359, 95% CI 1.344-1.373, p=<0.001). The weekend-admission/discharge pattern was associated with a 35.9% higher odds of in-hospital mortality compared to weekday-admission-discharge among older adults.
Synapse has enriched 10 related papers. Consider them for comparative context: