Key result
Withholding anticoagulation in patients with suspected pulmonary embolism and a negative helical CT resulted in a low 3-month risk of venous thromboembolic events (1.7%; 95% CI, 0.0%-3.2%).
Why the study?
Does withholding anticoagulation after a negative helical CT result in a low risk of venous thromboembolic events in patients with suspected acute pulmonary embolism?
Cohort (n=243)
Does withholding anticoagulation after a negative helical CT result in a low risk of venous thromboembolic events in patients with suspected acute pulmonary embolism?
A negative helical CT in patients with suspected pulmonary embolism is associated with a low 3-month risk of venous thromboembolism when anticoagulation is withheld.
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Supports withholding anticoagulation after negative helical CT; leaves open randomized confirmation of safety.
Donato et al. (2003) conducted a cohort in Suspected Acute Pulmonary Embolism (n=243). Negative helical CT followed by withholding anticoagulation was evaluated on Venous thromboembolic events (95% CI 0.0%-3.2%). Withholding anticoagulation in patients with suspected pulmonary embolism and a negative helical CT resulted in a low 3-month risk of venous thromboembolic events (1.7%; 95% CI, 0.0%-3.2%).
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