Key result
Myocardial stiffness was significantly correlated with plasma BNP levels in patients with both diastolic (P=0.004) and systolic (P=0.003) heart failure.
Why the study?
Does myocardial stiffness correlate with plasma BNP levels in patients with diastolic and systolic heart failure?
Observational (n=49)
Does myocardial stiffness correlate with plasma BNP levels in patients with diastolic and systolic heart failure?
p-value: p=0.004 (DHF), 0.003 (SHF)
Myocardial stiffness is a major determinant of steady-state plasma BNP production in both diastolic and systolic heart failure.
No takes yet. Share an insight, caveat, or question.
May explain BNP heterogeneity in HF; leaves open causal role of stiffness and therapeutic implications.
Watanabe et al. (2006) conducted an observational in Diastolic and systolic heart failure (n=49). Myocardial stiffness (Km) assessment vs. Controls was evaluated on Correlation between plasma BNP level and myocardial stiffness (Km) (p=0.004 (DHF), 0.003 (SHF)). Myocardial stiffness was significantly correlated with plasma BNP levels in patients with both diastolic (P=0.004) and systolic (P=0.003) heart failure.
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