Key result
Insulin resistance linked to ~8-fold higher LVH risk in asymptomatic Black African hypertensive patients.
Why the study?
Conflicting information exists regarding the association between insulin resistance and left ventricular hypertrophy.
Does insulin resistance increase the risk of left ventricular hypertrophy in asymptomatic Black sub-Saharan African hypertensive patients?
Case-Control (n=220)
No
Does insulin resistance increase the risk of left ventricular hypertrophy in asymptomatic Black sub-Saharan African hypertensive patients?
Effect estimate: aOR 8.4 (95% CI 3.7-15.7)
p-value: p=<0.001
Insulin resistance and obesity are strong, independent predictors of left ventricular hypertrophy in Black sub-Saharan African patients with essential hypertension.
No takes yet. Share an insight, caveat, or question.
May support IR screening in Black African hypertensives; leaves open whether IR reduction prevents LVH.
Phanzu et al. (2021) conducted a case-control in Essential hypertension (n=220). Insulin resistance vs. No insulin resistance was evaluated on Left ventricular hypertrophy (aOR 8.4, 95% CI 3.7-15.7, p=<0.001). Insulin resistance increased the risk of left ventricular hypertrophy by eightfold (aOR 8.4) in asymptomatic, Black, sub-Saharan African hypertensive patients.
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