What is the clinical evidence from this study?

Study design: Observational. Population: Normal and hypertrophied human hearts. Intervention: Post mortem microradiography vs. Normal hearts. Primary outcome: Arterial vascular pattern and calibre.

What does this research mean for the field?

Branching and straight type arteries in the left ventricular freewall of hypertrophied human hearts are of smaller calibre than those in normal hearts, and the vascular pattern is similar between concentric and asymmetrical hypertrophy. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To examine and compare the myocardial arterial architecture of the left ventricular freewall in normal human hearts and hearts with hypertrophy.

January 1, 1984Medicine Science and the Law

Observations on the Vascular Pattern of the Left Ventricular Freewall in Normal and Hypertrophied Hearts

View Full Paper

Ask AI

Bookmark

Key result

Post mortem microradiography showed that branching and straight type arteries in hypertrophied human hearts were of smaller calibre than in normal hearts.

Population

Post mortem normal and hypertrophied human hearts

Design

Other

Authors

WOW O OdesanmiEkiti State University

Discussion

Member takes

Implication

May increase ischemia risk in hypertrophy; leaves open functional significance and therapeutic implications.

Key Points

To examine and compare the myocardial arterial architecture of the left ventricular freewall in normal human hearts and hearts with hypertrophy.
Injected the coronary vasculature post-mortem with the radio-opaque medium Colourpaque in normal and hypertrophied human hearts.
Prepared and examined microradiographs of transverse ventricular slices using an immersion technique.
Branching-type arteries supplied the myocardial wall and subendocardial zone, whereas straight-type arteries supplied the papillary muscles and trabeculae carneae.
Both branching and straight arterial vessels showed smaller calibres in hypertrophied hearts compared with normal hearts.
The arterial vascular pattern in concentric left ventricular hypertrophy was qualitatively similar to that seen in asymmetrical left ventricular hypertrophy.

Study Design

Type

Observational

Structured PICO

Population

Post mortem normal and hypertrophied human hearts

Comparator

Normal human hearts

Outcome

Arterial vascular pattern and calibre of branching and straight type arteriessurrogate

Hypertrophied human hearts exhibit smaller calibre branching and straight type arteries compared to normal hearts, regardless of whether the hypertrophy is concentric or asymmetrical.

Cite This Study

W O Odesanmi (1984) conducted an observational in Normal and hypertrophied human hearts. Post mortem microradiography vs. Normal hearts was evaluated on Arterial vascular pattern and calibre. Post mortem microradiography showed that branching and straight type arteries in hypertrophied human hearts were of smaller calibre than in normal hearts.

synapsesocial.com/papers/6a180bcfd990e918e6b4d458 https://doi.org/10.1177/002580248402400108

View Full Paper

Ask AI

Bookmark

Observations on the Vascular Pattern of the Left Ventricular Freewall in Normal and Hypertrophied Hearts

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

Observations on the Vascular Pattern of the Left Ventricular Freewall in Normal and Hypertrophied Hearts

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

Also Consider

Also Consider