Key result
In patients with hypertrophic cardiomyopathy, percent wall thickening in systole was significantly reduced in relation to the severity of wall hypertrophy, measuring 14±8% in walls over 20 mm compared to 56±36% in walls 13-15 mm.
Cross-Sectional (n=51)
No
Absolute Event Rate: 14% vs 56%
p-value: p=<0.01
Electron beam computed tomography demonstrates that wall motion dynamics (percent wall thickening) are significantly reduced in proportion to the degree of wall thickness in patients with hypertrophic cardiomyopathy.
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Reduced wall thickening predominates in hypertrophic segments; hypothesis-generating for HCM phenotyping, requires prospective validation before clinical use.
Yoshida et al. (1997) conducted a cross-sectional in Hypertrophic cardiomyopathy (n=51). Severe wall hypertrophy (>20 mm) vs. Mild wall hypertrophy (13-15 mm) was evaluated on Percent wall thickening in systole (p=<0.01). In patients with hypertrophic cardiomyopathy, percent wall thickening in systole was significantly reduced in relation to the severity of wall hypertrophy, measuring 14±8% in walls over 20 mm compared to 56±36% in walls 13-15 mm.
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