What is the clinical evidence from this study?

Study design: RCT. Population: Healthy (n=20). Intervention: Ethanol vs. Sober (placebo drinks and pills). Primary outcome: Standard deviation of lateral position (SDLP; "weaving") (p=<0.001).

What does this research mean for the field?

Ethanol intake demonstrates a positive dose-response relationship with increased standard deviation of lateral position in both a driving simulator and on a real test track, validating the simulator as a sensitive measure of impaired driving. Novelty: ClaimNovelty.METHODOLOGICAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

January 28, 2013Accident Analysis & PreventionOpen Access

Comparison of driving simulator performance with real driving after alcohol intake: A randomised, single blind, placebo-controlled, cross-over trial

Q: What are the key findings of this study?

Ethanol intake demonstrated a positive dose-response relationship with increased standard deviation of lateral position in both the driving simulator and on a real test track (p<0.001 for both).

Q: What does this research mean for the field?

Ethanol intake demonstrates a positive dose-response relationship with increased standard deviation of lateral position in both a driving simulator and on a real test track, validating the simulator as a sensitive measure of impaired driving. Novelty: ClaimNovelty.METHODOLOGICAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

View Full Paper

Ask AI

Bookmark

Key result

Ethanol intake demonstrated a positive dose-response relationship with increased standard deviation of lateral position in both the driving simulator and on a real test track (p<0.001 for both).

Why the study?

Does ethanol affect driving performance in a simulator consistently with real driving?

Population

20 healthy male volunteers

Comparison

Ethanol titrated to blood alcohol concentration… vs Sober (placebo drinks and placebo pills)

Design

RCT, randomised, cross-over, single-blind

Follow-up

1h duration per trial

Authors

AHArne HellandNorwegian University of Science and Technology GJGunnar D. JenssenSINTEF LLLone-Eirin LervågSINTEF

Discussion

Member takes

Overview

Driving simulators reliably detect ethanol impairment; confirms SDLP external validity as a surrogate for real-world driving studies.

Study Design

Type

RCT (n=20)

Blinding

Single-blind

Randomization

Cross-over

Structured PICO

Does ethanol affect driving performance in a simulator consistently with real driving?

Population

20 healthy male volunteers

Intervention

Ethanol titrated to blood alcohol concentration (BAC) levels of 0.5g/L and 0.9g/L

Comparator

Sober (placebo drinks and placebo pills)

Outcome

Standard deviation of lateral position (SDLP; "weaving")surrogate

Main Result

p-value: p=<0.001

SDLP in a driving simulator is a sensitive measure of ethanol-impaired driving, showing relative external validity compared to real driving.

Limitations

Lack of perceived danger in the simulator may cause reckless driving and striking dissimilarities in a few test subjects compared to real driving.
Lack of perceived danger in the simulator causing reckless driving in a few test subjects

Cite This Study

Helland et al. (2013) conducted an RCT in Healthy (n=20). Ethanol vs. Sober (placebo drinks and pills) was evaluated on Standard deviation of lateral position (SDLP; "weaving") (p=<0.001). Ethanol intake demonstrated a positive dose-response relationship with increased standard deviation of lateral position in both the driving simulator and on a real test track (p<0.001 for both).

synapsesocial.com/papers/6a181e8eaeefdf6d9c1360a0 https://doi.org/10.1016/j.aap.2012.12.042

View Full Paper

Ask AI

Bookmark

January 28, 2013Accident Analysis & PreventionOpen Access

Comparison of driving simulator performance with real driving after alcohol intake: A randomised, single blind, placebo-controlled, cross-over trial

View Full Paper

Ask AI

Bookmark

Key result

Ethanol intake demonstrated a positive dose-response relationship with increased standard deviation of lateral position in both the driving simulator and on a real test track (p<0.001 for both).

Why the study?

Does ethanol affect driving performance in a simulator consistently with real driving?

Population

20 healthy male volunteers

Comparison

Ethanol titrated to blood alcohol concentration… vs Sober (placebo drinks and placebo pills)

Design

RCT, randomised, cross-over, single-blind

Follow-up

1h duration per trial

Authors

AHArne HellandNorwegian University of Science and Technology GJGunnar D. JenssenSINTEF LLLone-Eirin LervågSINTEF

Discussion

Member takes

Overview

Driving simulators reliably detect ethanol impairment; confirms SDLP external validity as a surrogate for real-world driving studies.

Study Design

Type

RCT (n=20)

Blinding

Single-blind

Randomization

Cross-over

Structured PICO

Does ethanol affect driving performance in a simulator consistently with real driving?

Population

20 healthy male volunteers

Intervention

Ethanol titrated to blood alcohol concentration (BAC) levels of 0.5g/L and 0.9g/L

Comparator

Sober (placebo drinks and placebo pills)

Outcome

Standard deviation of lateral position (SDLP; "weaving")surrogate

Main Result

p-value: p=<0.001

SDLP in a driving simulator is a sensitive measure of ethanol-impaired driving, showing relative external validity compared to real driving.

Limitations

Lack of perceived danger in the simulator may cause reckless driving and striking dissimilarities in a few test subjects compared to real driving.
Lack of perceived danger in the simulator causing reckless driving in a few test subjects

Cite This Study

synapsesocial.com/papers/6a181e8eaeefdf6d9c1360a0 https://doi.org/10.1016/j.aap.2012.12.042

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

View Full Paper

Ask AI

Bookmark