Key result
Ethanol and drug-ethanol combinations impair drunkenness test performance more than single or combined drugs.
Why the study?
Data about the effects of psychotropic drugs on the clinical test for drunkenness are limited.
Do single doses of psychotropic drugs, ethanol, or their combinations impair performance on the clinical test for drunkenness compared to placebo?
Comparison
Single doses of psychotropic drugs, ethanol, and their combinations versus placebo
Design
Randomized double-blind cross-over trials
Follow-up
5 hours
Authors
Loading...
Ethanol or drug-ethanol combinations warrant extra caution in performance evaluations; confirms the test's greater sensitivity versus moderate psychotropic drugs alone.
RCT (n=24)
Double-blind
Cross-over
Do single doses of psychotropic drugs, ethanol, or their combinations impair performance on the clinical test for drunkenness compared to placebo?
The clinical test for drunkenness is more sensitive to ethanol and drug-ethanol combinations than to moderate doses of psychotropic drugs alone.
Tapio Kuitunen (1994) reported an RCT. Psychotropic drugs and ethanol vs. Placebo was evaluated on Performance on the clinical test for drunkenness and laboratory tests (digit symbol substitution, simulated driving, global psychomotor performance). Single doses of ethanol or drug-ethanol combinations impaired performance on the clinical test for drunkenness more than moderate doses of single drugs or drug-drug combinations.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: