Why the study?
Does acute reduction in hematocrit and blood viscosity alter flow-mediated vasodilation in humans?
Population
12 subjects with hemochromatosis
Comparison
Removal of 500 mL of blood with concomitant… vs Baseline measurements before blood removal
Design
Other
Authors
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Reduced viscosity attenuates FMD independent of flow; challenges flow-only endothelial assessment and leaves open viscosity-adjusted FMD interpretation.
Does acute reduction in hematocrit and blood viscosity alter flow-mediated vasodilation in humans?
Blood viscosity significantly influences flow-mediated vasodilation, suggesting that assessing endothelial function solely by blood flow changes may be inaccurate.
Giannattasio et al. (2002) studied this question.
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