Key result
Endocardial biventricular stimulation via a transseptal approach decreased QRS duration from 184 to 108 ms and improved NYHA functional class to II in all 6 patients.
Why the study?
Does biventricular pacing using a totally endocardial approach improve clinical outcomes and symptoms in patients with end-stage cardiac failure?
Population
6 patients with nonischemic cardiomyopathy, mean age 60 +/- 9.6 years, women, in NYHA functional class III…
Design
Case_series
Follow-up
85 +/- 5 months
Authors
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Hypothesis-generating for transseptal endocardial BiV pacing in end-stage HF; larger trials needed before clinical adoption.
Observational (n=6)
Does biventricular pacing using a totally endocardial approach improve clinical outcomes and symptoms in patients with end-stage cardiac failure?
Long-term endocardial biventricular stimulation via a transseptal approach appears safe and effective in improving QRS duration and NYHA class in a small cohort of patients with end-stage heart failure.
Pasquié et al. (2007) conducted an observational in End-stage cardiac failure (n=6). Biventricular pacing using a totally endocardial approach was evaluated on QRS duration and NYHA functional class. Endocardial biventricular stimulation via a transseptal approach decreased QRS duration from 184 to 108 ms and improved NYHA functional class to II in all 6 patients.
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