Underlying left ventricular hypertrophy, previous myocardial infarction, and various ECG abnormalities were significantly more common in women with CAD-related sudden cardiac death (P<0.001).
Case-Control (n=610)
Underlying LVH, previous MI with scarring, and specific ECG abnormalities are important markers associated with CAD-related sudden cardiac death in women.
p-value: p=< 0.001
BACKGROUND: Sudden cardiac death (SCD) is a significant mode of death causing 15-20% of all deaths in high-income countries. Coronary artery disease (CAD) is the most common cause of SCD in both sexes, and SCD is often the first manifestation of underlying CAD in women. This case-control study aimed to determine the factors associated with SCD due to CAD in women. METHODS: = 610). To compare these groups, we used medical records, autopsy findings, echocardiograms, and electrocardiograms (ECGs). RESULTS: < 0.001). Various electrocardiographic abnormalities were more common in subjects with SCD, including higher heart rate, atrial fibrillation, prolonged QTc interval, wide or fragmented QRS complex and early repolarization. The prevalence of Q waves and T inversions did not differ between the groups. CONCLUSIONS: Underlying LVH and previous MI with myocardial scarring are common and often undiagnosed in women with CAD-related SCD. These results suggest that untreated CAD with concomitant myocardial disease is an important factor in SCD in women.
Hookana et al. (Thu,) conducted a case-control in Sudden cardiac death due to coronary artery disease (n=610). Sudden cardiac death due to CAD vs. Controls was evaluated on Factors associated with SCD due to CAD (p=< 0.001). Underlying left ventricular hypertrophy, previous myocardial infarction, and various ECG abnormalities were significantly more common in women with CAD-related sudden cardiac death (P<0.001).